PowderORX
Orexin-A & Orexin-B
Bulk≥99.5% Purity
Pharmaceutical-grade Orexin-A and Orexin-B for wakefulness and sleep disorder research.
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Pricing available for qualified medical professionals, clinics, and distributors.
Enquire NowDownload MonographView FAQMechanism of Action
Orexins (hypocretins) are hypothalamic neuropeptides critical for maintaining wakefulness. Orexin-A (33 aa) activates both OX1R and OX2R receptors, while Orexin-B (28 aa) preferentially binds OX2R. They stabilise wake states, regulate feeding behaviour, and modulate reward pathways. Orexin neuron loss causes narcolepsy type 1.
Clinical Benefits
- Regulates wakefulness and sleep-wake transitions
- Modulates appetite and feeding behaviour
- Supports energy homeostasis
- Research applications in narcolepsy and sleep disorders
Specifications
ComponentsOrexin-A (33 aa) + Orexin-B (28 aa)
Purity≥99.5% (HPLC verified)
TargetOX1R / OX2R receptors
Storage & Handling
- Store at -20°C
- Protect from light
For professional medical use only. Not for retail sale to the general public. Pricing available on request for qualified medical institutions and distributors.